Phytochemical composition and in vitro functional properties of three wild rose hips and their traditional preserves
Нема приказа
Аутори
Nadpal, Jelena D.![](/themes/MirageREDUN/images/orcid.png)
Lesjak, Marija
![](/themes/MirageREDUN/images/orcid.png)
Mrkonjić, Zorica
![](/themes/MirageREDUN/images/orcid.png)
Majkić, Tatjana M.
![](/themes/MirageREDUN/images/orcid.png)
Cetojević-Simin, Dragana D.
![](/themes/MirageREDUN/images/orcid.png)
Mimica-Dukić, Neda
![](/themes/MirageREDUN/images/orcid.png)
Beara, Ivana
![](/themes/MirageREDUN/images/orcid.png)
Чланак у часопису (Објављена верзија)
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Метаподаци
Приказ свих података о документуАпстракт
The aim of the present study was investigation of the phenolic profile, ascorbic acid content, antioxidant, anti-acetylcholinesterase, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree and jam) of three insufficiently examined Rosa species: Rosa dumalis Bechst., R. dumetorum Thuill. and R. sempervirens L. The liquid chromatography-tandem mass spectrometry analysis resulted in quantification of 14 of the 45 phenolic compounds examined, with ellagic acid as the most dominant. Notable antioxidant activity of all three species was confirmed through several assays. Moderate inhibition of acetylcholinesterase by extracts of all investigated Rosa species was observed. Several extracts of examined Rosa species demonstrated inhibition potency towards production of some monitored eicosanoids in cyclooxygenase-1 and 12-lipoxygenase pathways. Two R. sempervirens extracts exerted cytotoxic activity against HeLa and HT-29 cell lines, but were inactive towards MRC-5 and M...CF7. The results support the potential of these rose hips as food with health-promoting properties.
Кључне речи:
Rosa sempervirens L. / Rosa dumetorum Thuill / Rosa dumalis Bechst / LC-MS/MS / Cytotoxic activity / Antioxidant activity / Anti-inflammatory activity / Anti-acetylcholinesterase activityИзвор:
Food Chemistry, 2018, 241, 290-300Издавач:
- ELSEVIER SCI LTD, OXFORD
Финансирање / пројекти:
- Биолошки активни природни производи као потенцијални извори нових лекова и дијететских суплемената (RS-MESTD-Basic Research (BR or ON)-172058)
DOI: 10.1016/j.foodchem.2017.08.111
ISSN: 0308-8146
PubMed: 28958531
WoS: 000411624400036
Scopus: 2-s2.0-85028960490
Институција/група
Fakultet ekološke poljoprivredeTY - JOUR AU - Nadpal, Jelena D. AU - Lesjak, Marija AU - Mrkonjić, Zorica AU - Majkić, Tatjana M. AU - Cetojević-Simin, Dragana D. AU - Mimica-Dukić, Neda AU - Beara, Ivana PY - 2018 UR - https://redun.educons.edu.rs/handle/123456789/348 AB - The aim of the present study was investigation of the phenolic profile, ascorbic acid content, antioxidant, anti-acetylcholinesterase, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree and jam) of three insufficiently examined Rosa species: Rosa dumalis Bechst., R. dumetorum Thuill. and R. sempervirens L. The liquid chromatography-tandem mass spectrometry analysis resulted in quantification of 14 of the 45 phenolic compounds examined, with ellagic acid as the most dominant. Notable antioxidant activity of all three species was confirmed through several assays. Moderate inhibition of acetylcholinesterase by extracts of all investigated Rosa species was observed. Several extracts of examined Rosa species demonstrated inhibition potency towards production of some monitored eicosanoids in cyclooxygenase-1 and 12-lipoxygenase pathways. Two R. sempervirens extracts exerted cytotoxic activity against HeLa and HT-29 cell lines, but were inactive towards MRC-5 and MCF7. The results support the potential of these rose hips as food with health-promoting properties. PB - ELSEVIER SCI LTD, OXFORD T2 - Food Chemistry T1 - Phytochemical composition and in vitro functional properties of three wild rose hips and their traditional preserves EP - 300 SP - 290 VL - 241 DO - 10.1016/j.foodchem.2017.08.111 UR - conv_907 ER -
@article{ author = "Nadpal, Jelena D. and Lesjak, Marija and Mrkonjić, Zorica and Majkić, Tatjana M. and Cetojević-Simin, Dragana D. and Mimica-Dukić, Neda and Beara, Ivana", year = "2018", abstract = "The aim of the present study was investigation of the phenolic profile, ascorbic acid content, antioxidant, anti-acetylcholinesterase, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree and jam) of three insufficiently examined Rosa species: Rosa dumalis Bechst., R. dumetorum Thuill. and R. sempervirens L. The liquid chromatography-tandem mass spectrometry analysis resulted in quantification of 14 of the 45 phenolic compounds examined, with ellagic acid as the most dominant. Notable antioxidant activity of all three species was confirmed through several assays. Moderate inhibition of acetylcholinesterase by extracts of all investigated Rosa species was observed. Several extracts of examined Rosa species demonstrated inhibition potency towards production of some monitored eicosanoids in cyclooxygenase-1 and 12-lipoxygenase pathways. Two R. sempervirens extracts exerted cytotoxic activity against HeLa and HT-29 cell lines, but were inactive towards MRC-5 and MCF7. The results support the potential of these rose hips as food with health-promoting properties.", publisher = "ELSEVIER SCI LTD, OXFORD", journal = "Food Chemistry", title = "Phytochemical composition and in vitro functional properties of three wild rose hips and their traditional preserves", pages = "300-290", volume = "241", doi = "10.1016/j.foodchem.2017.08.111", url = "conv_907" }
Nadpal, J. D., Lesjak, M., Mrkonjić, Z., Majkić, T. M., Cetojević-Simin, D. D., Mimica-Dukić, N.,& Beara, I.. (2018). Phytochemical composition and in vitro functional properties of three wild rose hips and their traditional preserves. in Food Chemistry ELSEVIER SCI LTD, OXFORD., 241, 290-300. https://doi.org/10.1016/j.foodchem.2017.08.111 conv_907
Nadpal JD, Lesjak M, Mrkonjić Z, Majkić TM, Cetojević-Simin DD, Mimica-Dukić N, Beara I. Phytochemical composition and in vitro functional properties of three wild rose hips and their traditional preserves. in Food Chemistry. 2018;241:290-300. doi:10.1016/j.foodchem.2017.08.111 conv_907 .
Nadpal, Jelena D., Lesjak, Marija, Mrkonjić, Zorica, Majkić, Tatjana M., Cetojević-Simin, Dragana D., Mimica-Dukić, Neda, Beara, Ivana, "Phytochemical composition and in vitro functional properties of three wild rose hips and their traditional preserves" in Food Chemistry, 241 (2018):290-300, https://doi.org/10.1016/j.foodchem.2017.08.111 ., conv_907 .